A gunman killed five Amish girls before committing suicide in a one-room schoolhouse in Nickel Mines, Pennsylvania.

On October 2, 2006, a shooting occurred at the West Nickel Mines School, an Amish one-room schoolhouse in the Old Order Amish community of Nickel Mines, a village in Bart Township, Pennsylvania. Gunman Charles Carl Roberts IV took hostages and shot ten girls, killing six, before committing suicide in the schoolhouse. The emphasis on forgiveness and reconciliation in the Amish community's response was widely discussed by the national media. The West Nickel Mines School was later demolished, and a new one-room schoolhouse, the New Hope School, was built at another location. It is the worst school shooting in Pennsylvania history.

The Amish, formally the Old Order Amish, are a group of traditionalist Anabaptist Christian church fellowships with Swiss and Alsatian origins. As they maintain a degree of separation from surrounding populations, and hold their faith in common, the Amish have been described by certain scholars as an ethnoreligious group, combining features of an ethnicity and a Christian denomination. The Amish are closely related to Old Order Mennonites and Conservative Mennonites, denominations that are also a part of Anabaptist Christianity. The Amish are known for simple living, plain dress, Christian pacifism, and slowness to adopt many conveniences of modern technology, with a view neither to interrupt family time, nor replace face-to-face conversations whenever possible, and a view to maintain self-sufficiency. The Amish value rural life, manual labor, humility and Gelassenheit.

One-room schoolhouses, or One-room schools, have been commonplace throughout rural portions of various countries, including Prussia, Norway, Sweden, the United States, Canada, Australia, New Zealand, the United Kingdom, Ireland, Portugal, and Spain. In most rural and small town schools, all of the students meet in a single room. There, a single teacher teaches academic basics to several grade levels of elementary-age children. Recent years have seen a revival of the format. One-room schoolhouses can also be found in developing nations and rural or remote areas undergoing colonization.