The first and second of three treaties were signed near Medicine Lodge, Kansas, between the United States federal government and several Native American tribes in the Great Plains, requiring them to relocate to areas in present-day western Oklahoma.

The Medicine Lodge Treaty is the overall name for three treaties signed near Medicine Lodge, Kansas, between the Federal government of the United States and southern Plains Indian tribes in October 1867, intended to bring peace to the area by relocating the Native Americans to reservations in Indian Territory and away from European-American settlement. The treaty was negotiated after investigation by the Indian Peace Commission, which in its final report in 1868 concluded that the wars had been preventable. They determined that the United States government and its representatives, including the United States Congress, had contributed to the warfare on the Great Plains by failing to fulfill their legal obligations and to treat the Native Americans with honesty.

Medicine Lodge is a city in and the county seat of Barber County, Kansas, United States. As of the 2020 census, the population of the city was 1,781.

Plains Indians or Indigenous peoples of the Great Plains and Canadian Prairies are the Native American tribes and First Nations peoples who have historically lived on the Interior Plains of North America. While hunting-farming cultures have lived on the Great Plains for centuries prior to European contact, the region is known for the horse cultures that flourished from the 17th century through the late 19th century. Their historic nomadism and armed resistance to domination by the government and military forces of Canada and the United States have made the Plains Indian culture groups an archetype in literature and art for Native Americans everywhere.

Oklahoma is a landlocked state in the South Central and Southwestern region of the United States. It borders Texas to the south and west, Kansas to the north, Missouri to the northeast, Arkansas to the southeast, New Mexico to the west, and Colorado to the northwest. Partially in the western extreme of the Upland South, it is the 20th-most extensive and the 28th-most populous of the 50 United States. Its residents are known as Oklahomans and its capital and largest city is Oklahoma City.