A 7.5 magnitude earthquake strikes in the Hindu Kush mountain range in South Asia, killing 399 people and leaving 2,536 people injured.

The October 2015 Hindu Kush earthquake was a magnitude 7.5 earthquake that struck South Asia on 26 October 2015, at 13:39 AFT with the epicenter 45 km north of Kuran wa Munjan, Afghanistan, at a depth of 231.0 km.

The Hindu Kush is an 800-kilometre-long (500 mi) mountain range in Central and South Asia to the west of the Himalayas. It stretches from central and eastern Afghanistan into northwestern Pakistan and far southeastern Tajikistan. The range forms the western section of the Hindu Kush Himalayan Region (HKH); to the north, near its northeastern end, the Hindu Kush buttresses the Pamir Mountains near the point where the borders of China, Pakistan and Afghanistan meet, after which it runs southwest through Pakistan and into Afghanistan near their border.

South Asia is the southern subregion of Asia that is defined in both geographical and ethnic-cultural terms. South Asia, with a population of 2.04 billion, contains a quarter (25%) of the world's population. As commonly conceptualised, the modern states of South Asia include Bangladesh, Bhutan, India, the Maldives, Nepal, Pakistan, and Sri Lanka, with Afghanistan also often included, which may otherwise be classified as part of Central Asia. South Asia borders East Asia to the northeast, Central Asia to the northwest, West Asia to the west and Southeast Asia to the east. Apart from Southeast Asia, Maritime South Asia is the only subregion of Asia that lies partly within the Southern Hemisphere. The British Indian Ocean Territory and two out of 26 atolls of the Maldives in South Asia lie entirely within the Southern Hemisphere. Topographically, it is dominated by the Indian subcontinent and is bounded by the Indian Ocean in the south, and the Himalayas, Karakoram, and Pamir Mountains in the north.