A rocket carrying NASA's Cygnus CRS Orb-3 resupply mission to the International Space Station explodes seconds after taking off from the Mid-Atlantic Regional Spaceport in Wallops Island, Virginia.

Orbital-3, also known as Orb-3, was an attempted flight of Cygnus, an automated cargo spacecraft developed by United States–based company Orbital Sciences, on 28 October 2014. The mission was intended to launch at 22:22:38 UTC that evening. This flight, which would have been its fourth to the International Space Station and the fifth of an Antares launch vehicle, resulted in the Antares rocket exploding seconds after liftoff.

The International Space Station (ISS) is a large space station that was assembled and is maintained in low Earth orbit by a collaboration of five space agencies and their contractors: NASA, Roscosmos (Russia), ESA (Europe), JAXA (Japan), and CSA (Canada). As the largest space station ever constructed, it primarily serves as a platform for conducting scientific experiments in microgravity and studying the space environment.

The Mid-Atlantic Regional Spaceport (MARS) is a commercial space launch facility located at the southern tip of NASA's Wallops Flight Facility on Wallops Island in Virginia, just east of the Delmarva Peninsula and south of Chincoteague, Virginia, United States. It is owned and operated by the Virginia Spaceport Authority.

Wallops Island is a six-square-mile (16 km²) island in Accomack County, Virginia, part of the Virginia Barrier Islands that stretch along the eastern seaboard of the United States. It is just south of Chincoteague Island, a popular tourist destination.