After his terminal-cancer diagnosis, Warren Zevon made his last public appearance on the Late Show with David Letterman, giving the advice to "enjoy every sandwich".

Warren William Zevon was an American rock singer and songwriter. His most famous compositions include "Werewolves of London", "Lawyers, Guns and Money" and "Roland the Headless Thompson Gunner". All three songs are featured on his third album, Excitable Boy (1978), the title track of which is also well-known. He also wrote major hits that were recorded by other artists, including "Poor Poor Pitiful Me", "Mohammed's Radio", "Carmelita" and "Hasten Down the Wind". Per The New York Times, "Mr. Zevon had a pulp-fiction imagination" which yielded "terse, action-packed, gallows-humored tales that could sketch an entire screenplay in four minutes and often had death as a punchline. But there was also vulnerability and longing in Mr. Zevon's ballads, like 'Mutineer,' 'Accidentally Like a Martyr' and 'Hasten Down the Wind'."

Shortly after being diagnosed with terminal lung cancer, American singer-songwriter Warren Zevon made his final public appearance on the late-night talk show Late Show with David Letterman on October 30, 2002. Zevon, who had regularly appeared on the show over the preceding decade, was unusually given the majority of the episode to talk with Letterman and perform three songs. The episode is known for the humor that Zevon used throughout the interview, as well as his quip that his terminal diagnosis was a reminder to "enjoy every sandwich".

Late Show with David Letterman is an American late-night talk show hosted by David Letterman on CBS, the first iteration of the Late Show franchise. The show debuted on August 30, 1993, and was produced by Letterman's production company, Worldwide Pants, and CBS Television Studios. The show's music director and leader of the house band, the CBS Orchestra, was Paul Shaffer. The head writer was Matt Roberts and the announcer was originally Bill Wendell, then Alan Kalter. In most American markets the show aired from 11:35 p.m. to 12:37 a.m. Eastern and Pacific Time, and recorded Monday to Wednesdays at 4:30 p.m., and Thursdays at 3:30 p.m. and 6:00 p.m. Eastern Time. The second Thursday episode usually aired on Friday of that week.