The Israeli Air Force conducted missile strikes that hit multiple targets in western Syria, including one that accidentally downed a Russian plane.

The Israeli Air Force operates as the aerial and space warfare branch of the Israel Defense Forces (IDF). It was founded on May 28, 1948, shortly after the Israeli Declaration of Independence. As of April 2022, Aluf Tomer Bar has been serving as the Air Force commander.

On 17 September 2018, the Israeli Air Force (IAF) conducted missile strikes against multiple targets in government-controlled western Syria. Syrian air defences responded to the Israeli fighter jets, accidentally shooting a Russian military Il-20, killing 15 crew aboard. Russia blamed Israel for the loss of its plane, accusing the IAF of "hiding behind the Russian aircraft", thereby putting it in the line of fire. The Israel Defense Forces acknowledged striking a Syrian weapons facility, and expressed sorrow for the loss of lives due to Syrian fire. The strikes occurred a few hours after a Russo-Turkish agreement to create a demilitarized zone around Idlib Governorate was achieved, which postponed an imminent offensive operation by Syria's forces and its allies.