A dump truck full of explosives detonates in front of the Marriott hotel in Islamabad, Pakistan, killing 54 people and injuring 266 others.

The Islamabad Marriott Hotel bombing occurred on the night of 20 September 2008, when a dumper truck filled with explosives was detonated in front of the Marriott Hotel in the Pakistani capital Islamabad, killing at least 54 people, injuring at least 266 and leaving a 60 ft (18 m) wide, 20 ft (6.1 m) deep crater outside the hotel. The majority of the casualties were Pakistanis; at least five foreign nationals were also killed and fifteen others reported injured. The attack occurred only hours after President Asif Ali Zardari made his first speech to the Pakistani parliament. The Marriott was the most prestigious hotel in the capital, and was located near government buildings, diplomatic missions, embassies and high commissions.

September 20 is the 263rd day of the year in the Gregorian calendar; 102 days remain until the end of the year.