Pompey was killed by Lucius Septimius at Pelusium in Egypt.

Gnaeus Pompeius Magnus, known in English as Pompey or Pompey the Great, was a Roman general and statesman who was prominent in the last decades of the Roman Republic. As a young man, he was a partisan and protégé of the dictator Sulla, after whose death he achieved much military and political success himself. He was an ally and a rival of Julius Caesar, and died in civil war with him.

Lucius Septimius was a Roman soldier and mercenary who is principally remembered as one of the assassins of the triumvir Pompey the Great. At the time of the assassination in 48 BC, Septimius was serving the Ptolemies of Egypt as a mercenary. He was dispatched with orders to murder Pompey by Ptolemy XIII's advisors who wanted to win the favour of Julius Caesar for their king.

Pelusium was an important city in the eastern extremes of Egypt's Nile Delta, 30 km (19 mi) to the southeast of the modern Port Said. It became a Roman provincial capital and Metropolitan archbishopric and remained a multiple Catholic titular see and an Eastern Orthodox active archdiocese.