American Indian Wars: In Nebraska, 700 soldiers under United States General William S. Harney avenge the Grattan massacre by attacking a Sioux village and killing 100 men, women and children.

The American Indian Wars, also known as the American Frontier Wars, and the Indian Wars, was a conflict initially fought by European colonial empires, the United States, and briefly the Confederate States of America and Republic of Texas against various American Indian tribes in North America. These conflicts occurred from the time of the earliest colonial settlements in the 17th century until the end of the 19th century. The various wars resulted from a wide variety of factors, the most common being the desire of settlers and governments for Indian tribes' lands. The European powers and their colonies enlisted allied Indian tribes to help them conduct warfare against each other's colonial settlements. After the American Revolution, many conflicts were local to specific states or regions and frequently involved disputes over land use; some entailed cycles of violent reprisal.

Nebraska is a landlocked state in the Midwestern region of the United States. It borders South Dakota to the north; Iowa to the east and Missouri to the southeast, both across the Missouri River; Kansas to the south; Colorado to the southwest; and Wyoming to the west. Nebraska is the 16th-largest state by land area, with just over 77,220 square miles (200,000 km²). With a population of over 2 million as of 2024, it is the 38th-most populous state and the eighth-least densely populated. Its capital is Lincoln, and its most populous city is Omaha, which is on the Missouri River. Nebraska was admitted into the United States in 1867, two years after the end of the American Civil War. The Nebraska Legislature is unlike any other American legislature in that it is unicameral, and its members are elected without any official reference to political party affiliation. Nebraska is one of only two states that divide electoral college votes by district, and is not winner-take-all.

William Selby Harney, otherwise known among the Lakota as "Woman Killer" and "Mad Bear," was an American cavalry officer in the US Army, who became known during the Indian Wars and the Mexican–American War for his brutality and ruthlessness. One of five general officers in the US Army at the beginning of the American Civil War, he was removed from overseeing the Department of the West because of his Southern sympathies early in the war, although he kept Missouri from joining the Confederacy. Under President Andrew Johnson, he served on the Indian Peace Commission, negotiating in several treaties before spending his retirement partly in Missouri and partly trading reminiscences with Jefferson Davis and Ulysses S. Grant in Mississippi, eventually moving to Florida afterwards, where he spent the last few years of his life.