Pan Am Flight 73 from Mumbai, India with 358 people on board is hijacked at Karachi International Airport.

Pan Am Flight 73 was a Pan American World Airways flight from Bombay, India, to New York City, United States, with scheduled stops in Karachi, Pakistan, and Frankfurt, West Germany.

Mumbai, also known as Bombay, is the capital city of the Indian state of Maharashtra. Mumbai is the financial capital and the most populous city proper of India with an estimated population of 12.5 million (1.25 crore). Mumbai is the centre of the Mumbai Metropolitan Region, which is among the most populous metropolitan areas in the world with a population of over 23 million. Mumbai lies on the Konkan coast on the west coast of India and has a deep natural harbour. In 2008, Mumbai was named an alpha world city. Mumbai has the highest number of billionaires out of any city in Asia.

Aircraft hijacking is the unlawful seizure of an aircraft by an individual or a group. Dating from the earliest of hijackings, most cases involve the pilot being forced to fly according to the hijacker's demands. There have also been incidents where the hijackers have overpowered the flight crew, made unauthorized entry into the cockpit and flown them into buildings—most notably in the September 11 attacks—and in some cases, planes have been hijacked by the official pilot or co-pilot, such as with Ethiopian Airlines Flight 702.

Jinnah International Airport, formerly Drigh Road Airport or Karachi International Airport, is Pakistan's busiest international and domestic airport, and handled 7,267,582 passengers in 2017–2018. Located in Karachi, the largest city and commercial capital of Pakistan and capital of the province of Sindh, it is named after Muhammad Ali Jinnah, the statesman founder of Pakistan.