Gothic War: The Ostrogoths, under King Totila, conquer Rome after a long siege, by bribing the Isaurian garrison.

The Gothic War between the Byzantine Empire during the reign of Emperor Justinian I and the Ostrogothic Kingdom of Italy took place from 535 to 554 in the Italian peninsula, Dalmatia, Sardinia, Sicily, and Corsica. It was one of the last of the many Gothic wars against the Roman Empire. The war had its roots in the ambition of the Byzantine emperor Justinian I to recover the provinces of the former Western Roman Empire, which the Romans had lost to invading barbarian tribes in the previous century, during the Migration Period.

The Ostrogoths were a Roman-era Germanic people. In the 5th century, they followed the Visigoths in creating one of the two great Gothic kingdoms within the Western Roman Empire, drawing upon the large Gothic populations who had settled in the Balkans in the 4th century. While the Visigoths had formed under the leadership of Alaric I, the new Ostrogothic political entity which came to rule Italy was formed in the Balkans under Theodoric the Great.

Totila, original name Baduila, was the penultimate King of the Ostrogoths, reigning from 541 to 552 AD. A skilled military and political leader, Totila reversed the tide of the Gothic War, recovering by 543 almost all the territories in Italy that the Eastern Roman Empire had captured from his Kingdom in 540.

Isauria, in ancient geography, is a rugged, isolated district in the interior of Asia Minor, of very different extent at different periods, but generally covering what is now the district of Bozkır and its surroundings in the Konya Province of Turkey, or the core of the Taurus Mountains. In its coastal extension it bordered on Cilicia.