Arab–Byzantine wars: Battle of Apamea: Fatimids defeat a Byzantine army near Apamea.

The Arab–Byzantine wars or Muslim–Byzantine wars were a series of wars from the 7th to 11th centuries between multiple Arab dynasties and the Byzantine Empire. The Muslim Arab Caliphates conquered large parts of the Christian Byzantine empire and unsuccessfully attacked the Byzantine capital of Constantinople. The frontier between the warring states remained almost static for three centuries of frequent warfare, before the Byzantines were able to recapture some of the lost territory.

The Battle of Apamea was fought on 19 July 998 between the forces of the Byzantine Empire and the Fatimid Caliphate. The battle was part of a series of military confrontations between the two powers over control of northern Syria and the Hamdanid emirate of Aleppo, which in turn were part of the larger series of regional conflicts known as the Arab–Byzantine wars. The Byzantine regional commander, Damian Dalassenos, had been besieging Apamea, until the arrival of the Fatimid relief army from Damascus, under Jaysh ibn Samsama. In the subsequent battle, the Byzantines were initially victorious, but a lone Kurdish rider managed to kill Dalassenos, throwing the Byzantine army into panic. The fleeing Byzantines were then pursued, with much loss of life, by the Fatimid troops. This defeat forced the Byzantine emperor Basil II to personally campaign in the region the next year, and was followed in 1001 by the conclusion of a ten-year truce between the two states.

The Fatimid Caliphate, also known as the Fatimid Empire, was a caliphate extant from the tenth to the twelfth centuries CE under the rule of the Fatimids, an Isma'ili Shi'a dynasty. Spanning a large area of North Africa and West Asia, it ranged from the western Mediterranean in the west to the Red Sea in the east. The Fatimids traced their ancestry to the Islamic prophet Muhammad's daughter Fatima and her husband Ali, the first Shi'a imam. The Fatimids were acknowledged as the rightful imams by different Isma'ili communities as well as by denominations in many other Muslim lands and adjacent regions. Originating during the Abbasid Caliphate, the Fatimids initially conquered Ifriqiya. They extended their rule across the Mediterranean coast and ultimately made Egypt the center of the caliphate. At its height, the caliphate included—in addition to Egypt—varying areas of the Maghreb, Sicily, the Levant, and the Hejaz.